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BAY 2416964

CAS No. 2242464-44-2

BAY 2416964( —— )

Catalog No. M22445 CAS No. 2242464-44-2

BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	87	In Stock
10MG	152	In Stock
25MG	311	In Stock
50MG	447	In Stock
100MG	588	In Stock
200MG	836	In Stock
500MG	1251	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

BAY 2416964
Note

Research use only, not for human use.
Brief Description

BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).
Description

BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Aryl hydrocarbon receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

2242464-44-2
Formula Weight

387.82
Molecular Formula

C18H18ClN5O3
Purity

>98% (HPLC)
Solubility

DMSO:250 mg/mL (644.63 mM; Need ultrasonic)
SMILES

C[C@@H](CO)NC(=O)c1cc(nn(-c2cnn(C)c2)c1=O)-c1ccc(Cl)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Ilona GUTCHER, et al. 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer. WO2018146010A1.

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