Cart
sales@molnova.com
BAY 2416964
CAS No. 2242464-44-2
BAY 2416964 ( —— )
Catalog No. M22445 CAS No. 2242464-44-2
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 87 | In Stock |
|
| 10MG | 152 | In Stock |
|
| 25MG | 311 | In Stock |
|
| 50MG | 447 | In Stock |
|
| 100MG | 588 | In Stock |
|
| 200MG | 836 | In Stock |
|
| 500MG | 1251 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBAY 2416964
-
NoteResearch use only, not for human use.
-
Brief DescriptionBAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).
-
DescriptionBAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorAryl hydrocarbon receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2242464-44-2
-
Formula Weight387.82
-
Molecular FormulaC18H18ClN5O3
-
Purity>98% (HPLC)
-
SolubilityDMSO:250 mg/mL (644.63 mM; Need ultrasonic)
-
SMILESC[C@@H](CO)NC(=O)c1cc(nn(-c2cnn(C)c2)c1=O)-c1ccc(Cl)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ilona GUTCHER, et al. 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer. WO2018146010A1.
molnova catalog
related products
-
5,8-Epidioxyergosta-...
9,11-Dehydroergosterol peroxide is a useful organic compound for research related to life sciences.
-
L-Gulono-14-lactone
L-Gulono-14-lactone is a substrate of L-gulono-14-lactone oxidoreductase which catalyzes the last step of the biosynthesis of L-ascorbic (Vitamin) C.
-
Lophanthoidin E
Lophanthoidin E is a kind of natural product derived from the herbs of Rabdosia lophanthoides.
